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In a first-of-its-kind study by King's College London, researchers have linked changes in two major types of immune cells in blood to different survival outcomes for patients with melanoma.

Brain-resident immune cells that have reached an old-age state called "senescence" secrete a protein that causes dysfunction in other brain cells, according to a study led by investigators at Weill Cornell Medicine.

Having surgery for a heart condition is thought to have triggered an immune response that put the patient into remission for his severe skin cancer, but also caused him to develop a serious allergy to bee stings.

Researchers at National Jewish Health and partner institutions have discovered specific changes in immune cells in the lungs of people with sarcoidosis.

The brain's immune cells are increasingly recognized as key players in Alzheimer's disease, but exactly how they change as the disease develops has remained unclear. A new study published in Nature Genetics provides the most comprehensive map to date of these cells, identifying a

HIV (human immunodeficiency virus) is a virus that attacks the body's immune system and remains a major global health challenge because of persistent viral reservoirs, despite effective treatments. Key factors include around 40 million people living with HIV, 1 million new infect

A tumor is more than its cancer cells. Immune cells, blood vessels and other surrounding tissue influence how a cancer grows and responds to treatment. Two tumors containing the same cell types can respond very differently to the same therapy depending on how those cells are arra

For most healthy people, Cryptococcus is an unnoticed infection. The immune system walls it off in the lungs and keeps it dormant for life. But in patients undergoing cancer chemotherapy, recovering from an organ transplant, living with HIV or taking newer immunosuppressing drugs

The early period of life is a critical phase in which the immune system must learn to tolerate harmless environmental stimuli, such as food and microbes that normally live in and on the body, while remaining vigilant against harmful substances and pathogens. If it fails to strike

An international team of researchers has developed an innovative strategy for producing new vaccines. They created a genetically modified version of the chikungunya virus that replicates only once yet still trains the immune system to defend itself without causing disease. In tes

Beginning around age 50, the brain’s memory center appears to lose many of its longtime immune cells and replace them with more inflammatory ones. This surprising shift may help explain how normal aging sets the stage for Alzheimer’s disease and dementia.

Every time a virus invades a person, it collides with thousands of years of human history. A study led by researchers at the USC Dornsife College of Letters, Arts and Sciences and Howard University suggests that some of the genes involved in the body's immune response today bear